Enhanced Stability of Polymeric Micelles Based on Postfunctionalized Poly(ethylene glycol)-b-poly(y-propargyl L-glutamate): The Substituent Effect
- Auteur
- XIAOYONG ZHAO1 ; POON, Zhiyong1 ; ENGLER, Amanda C1 ; BONNER, Daniel K1 ; HAMMOND, Paula T1
[1] Department of Chemical Engineering, Massachusetts Institute of Technology and the Koch Institute for Integrative Cancer Research at MIT, Cambridge, Massachusetts 02139, United States - Source
Biomacromolecules. 2012, Vol 13, Num 5, pp 1315-1322, 8 p ; ref : 32 ref
- ISSN
- 1525-7797
- Domaine scientifique
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Editeur
- American Chemical Society, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Azide Cinétique Concentration critique micellaire Copolymère biséquencé Cycloaddition dipolaire 1,3 Cytotoxicité Effet substituant Ethylène oxyde copolymère Etude expérimentale Glutamate copolymère In vitro Libération Lignée HeLa Modification chimique Nanoencapsulation Paclitaxel Polymère amphiphile Polymère monodispersé Polymère vecteur Polymérisation ouverture cycle Préparation Solution aqueuse Solution micellaire Triazole dérivé copolymère Vecteur médicament Chimie clic Glutamate de gamma propargyle copolymère Stabilité cinétique Peptide copolymère Propriété biologique
- Mot clé (en)
- Organic azide Kinetics Micellar critical concentration Diblock copolymer 1,3-Dipolar cycloaddition Cytotoxicity Substituent effect Ethylene oxide copolymer Experimental study Glutamate copolymer In vitro Release Hela cell line Chemical modification Nanoencapsulation Paclitaxel Amphiphilic polymer Monodispersed polymer Control release polymer Ring opening polymerization Preparation Aqueous solution Micellar solution Triazole derivative copolymer Drug carrier Aminoacid copolymer Biological properties
- Mot clé (es)
- Azida orgánica Cinética Concentración crítica micelar Copolímero bisecuencia 1,3-Dipolar cicloadición Citotoxicidad Efecto sustituyente Etileno óxido copolímero Estudio experimental Glutamato copolímero In vitro Liberación Célula HeLa Modificación química Nanoencapsulación Paclitaxel Polímero amfifilo Polímero monodispersado Polímero vector Polimerización abertura ciclo Preparación Solución acuosa Solución micelar Triazol derivado copolímero Vector medicamento Péptido copolímero Propiedad biológica
- Classification
- Pascal
- 001 Sciences exactes et technologie / 001D Sciences appliquees / 001D09 Physicochimie des polymeres / 001D09F Biopolymères de synthèse / 001D09F02 Polyaminoacides
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02A Pharmacologie générale / 002B02A03 Technologie pharmaceutique. Industrie pharmaceutique
- Discipline
- General pharmacology Physical chemistry of polymers
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 25888363
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm201873u 
https://dx.doi.org/10.1021/bm201873u
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