Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
- Auteur
- JAIN, Mohit1 2 3 4 ; NILSSON, Roland1 2 3 5 ; SHARMA, Sonia6 ; MADHUSUDHAN, Nikhil1 2 3 ; KITAMI, Toshimori1 2 3 ; SOUZA, Amanda L1 ; KAFRI, Ran2 ; KIRSCHNER, Marc W2 ; CLISH, Clary B1 ; MOOTHA, Vamsi K1 2 3
[1] Broad Institute, Cambridge, MA 02142, United States
[2] Department of Systems Biology, Harvard Medical School, Boston, MA 02115, United States
[3] Center for Human Genetic Research and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, United States
[4] Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States
[5] Unit of Computational Medicine, Department of Medicine, Karolinska Institutet, 17176 Stockholm, Sweden
[6] La Jolla Institute for Allergy & Immunology, La Jolla, CA 92037, United States - Source
Science (Washington, D.C.). 2012, Vol 336, Num 6084, pp 1040-1044, 5 p
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Domaine scientifique
- Multidisciplinary
- Editeur
- American Association for the Advancement of Science, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Cancer Cancérologie Carcinogenèse Glycine Homme Lignée cellulaire établie Multiplication cellulaire Métabolite Tumeur maligne Lignée NCI 60 Aminoacide
- Mot clé (en)
- Cancer Cancerology Carcinogenesis Glycine Human Established cell line Cell proliferation Metabolite Malignant tumor Aminoacid
- Mot clé (es)
- Cáncer Cancerología Carcinogénesis Glicina Hombre Línea celular establecida Multiplicación celular Metabolito Tumor maligno Aminoácido
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B04 Tumeurs / 002B04E Carcinogenèse, carcinogènes et anticarcinogènes / 002B04E01 Généralités
- Discipline
- Tumours
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 25949300
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1218595 
https://dx.doi.org/10.1126/science.1218595
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