Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis
- Auteur
- RUPERTO, Nicolino1 ; BRUNNER, Hermine I4 ; SCHNEIDER, Rayfel20 ; BERKUN, Yackov12 ; CALVO, Inmaculada21 ; ERGUVEN, Muferet17 ; GOFFIN, Laurence23 ; HOFER, Michael25 ; KALLINICH, Tilmann10 ; OLIVEIRA, Sheila K18 ; UZIEL, Yosef13 ; VIOLA, Stefania1 ; QUARTIER, Pierre5 ; NISTALA, Kiran15 ; WOUTERS, Carine24 ; CIMAZ, Rolando3 ; FERRANDIZ, Manuel A; FLATO, Berit; LUZ GAMIR, Maria22 ; KONE-PAUT, Isabelle6 ; GROM, Alexei4 ; MAGNUSSON, Bo; OZEN, Seza; CONSTANTIN, Tamas7 ; SZTAJNBOK, Flavio; LHERITIER, Karine; ABRAMS, Ken; KIM, Dennis; MARTINI, Alberto1 2 ; LOVELL, Daniel J4 ; WULFFRAAT, Nico8 ; HORNEFF, Gerd9 ; BRIK, Riva11 ; MCCANN, Liza14 ; KASAPCOPUR, Ozgur16 ; RUTKOWSKA-SAK, Lidia19
[1] Istituto Giannina Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology International Trials Organisation (PRINTO) Coordinating Center, Italy
[2] Dipartimento di Pediatria, Università di Genova, Genoa, Italy
[3] Azienda Ospedaliero-Universitaria Meyer, Florence, Italy
[4] Division of Rheumatology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Pediatric Rheumatology Collaborative Study Group (PRCSG) Coordinating Center, Cincinnati, United States
[5] Unite d'Immunologie, Hématologie et Rhumatologie Pediatrique, Universite Paris-Descartes, Hôpital Necker-Enfants Malades, France
[6] Centre de Reference National des Maladies Auto-Inflammatoires, Rhumatologie Pediatrique, Centre Hospitalier Universitaire le Kremlin-Bicêtre, University of Paris Sud, Le Kremlin-Bicêtre, France
[7] Unit of Pediatric Rheumatology, Semmelweis University, Budapest, Hungary
[8] Department of Pediatric Immunology and Rheumatology, Wilhelmina Kinderziekenhuis, Utrecht, Netherlands
[9] Zentrum für Allgemeine Paediatrie und Neonatologie, Sankt Augustin, Germany
[10] Pediatric Pneumology and Immunology, Charité University Hospital Berlin, Berlin, Germany
[11] Department of Pediatrics, Rambam Medical Center, Haifa, Israel
[12] Department of Pediatrics, Hadassah Medical Center-Hadassah University Hospital Mount Scopus, Jerusalem, Israel
[13] Department of Pediatrics, Meir Medical Center, Kfar Saba, Israel
[14] Alder Hey Children's National Health Service Foundation Trust, Liverpool, United Kingdom
[15] Centre of Paediatric and Adolescent Rheumatology, Great Ormond Street Hospital, University College London, London, United Kingdom
[16] Pediatric Rheumatology, Cerrahpasa Medical Faculty, Istanbul University, Turkey
[17] Clinic of Pediatric Health and Diseases, Göztepe Education and Research Hospital, Istanbul, Turkey
[18] Department of Pediatric Nephrology and Rheumatology, Hacettepe University Children's Hospital, Ankara, Turkey
[19] Pediatric Clinic, Institute of Rheumatology, Warsaw, Poland
[20] Division of Rheumatology, Hospital for Sick Children, University of Toronto, Toronto, United States
[21] Pediatric Rheumatology Department, Hospital Universitario La Fe, Valencia, Spain
[22] Unidad de Reumatología Pediatrica, Hospital Ramon y Cajal, Madrid, Spain
[23] Service de Pediatrie, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium
[24] Department of Pediatrics, Division of Pediatric Rheumatology, University Hospital Gasthuisberg, Leuven, Belgium
[25] Pediatrie, Unité Romande de Rhumatologie Pediatrique, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, and Hôpitaux Universitaires de Geneve, Geneva, Switzerland
PRINTO and PRCSG - Source
The New England journal of medicine. 2012, Vol 367, Num 25, pp 2396-2406, 11 p ; ref : 42 ref
- CODEN
- NEJMAG
- ISSN
- 0028-4793
- Domaine scientifique
- General medicine general surgery
- Editeur
- Massachusetts Medical Society, Waltham, MA
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Arthrite chronique juvénile Canakinumab Chronique Disséminé Enfant Essai clinique Immunomodulateur Médecine Randomisation Systémique Anticorps monoclonal Homme Pathologie du système ostéoarticulaire Rhumatisme inflammatoire
- Mot clé (en)
- Juvenile rheumatoid arthritis Canakinumab Chronic Disseminated Child Clinical trial Immunomodulator Medicine Randomization Systemic Monoclonal antibody Human Diseases of the osteoarticular system Inflammatory joint disease
- Mot clé (es)
- Artritis crónica juvenil Canakinumab Crónico Diseminado Niño Ensayo clínico Inmunomodulador Medicina Aleatorización Sistémico Anticuerpo monoclonal Hombre Sistema osteoarticular patología Reumatismo inflamatorio
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B15 Pathologie osteoarticulaire / 002B15D Rhumatisme inflammatoire
- Discipline
- Generalities in medical sciences Osteoarticular pathology
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 26727156
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1056/NEJMoa1205099 
https://dx.doi.org/10.1056/NEJMoa1205099
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Accès par arXiv
