EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- Auteur
- KEXIN XU1 2 ; ZHENHUA JEREMY WU1 3 ; HAN XU1 3 ; CATO, Laura1 2 ; THORNTON, James E8 9 ; GREGORY, Richard I8 9 ; MORRISSEY, Colm10 ; VESSELLA, Robert L10 11 ; MONTIRONI, Rodolfo12 ; MAGI-GALLUZZI, Cristina13 ; KANTOFF, Philip W2 ; BALK, Steven P4 ; GRONER, Anna C1 2 ; LIU, X. Shirley1 3 ; BROWN, Myles1 2 ; HOUSHENG HANSEN HE1 2 3 ; CHANGMENG CAI4 ; LIS, Rosina T2 5 6 7 ; XIAOQIU WU2 5 ; STACK, Edward C2 5 6 7 ; LODA, Massimo2 5 6 7 ; TAO LIU1 3
[1] Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, United States
[2] Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, United States
[3] Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02115, United States
[4] Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, United States
[5] Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02115, United States
[6] Department of Pathology, Brigham and Women's Hospital, Harvard Medical School,, Boston, MA 02115, United States
[7] Division of Cancer Studies, King's College London, London SE1 8UB, United Kingdom
[8] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, United States
[9] Stem Cell Program, Children's Hospital, Boston, MA 02115, United States
[10] Department of Urology, University of Washington Medical Center, Seattle, WA 98195, United States
[11] Puget Sound VA Health Care System, Seattle, WA 98108, United States
[12] Section of Pathological Anatomy, Polytechnic University of Marche Region, United Hospitals, 60126 Torrette, Ancona, Italy
[13] Pathology and Laboratory Medicine Institute, Glickman Urological and Kidney Institute, Department of Cancer Biology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, United States - Source
Science (Washington, D.C.). 2012, Vol 338, Num 6113, pp 1465-1469, 5 p
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Domaine scientifique
- Multidisciplinary
- Editeur
- American Association for the Advancement of Science, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Cancer de la prostate Cancérologie Carcinogenèse Castration Gène onc cellulaire Homme Lignée cellulaire établie Néphrologie Résistance traitement Urologie Gène Ezh2 Gène PRC2 Lignée LNCaP Cancer Génétique Pathologie de l'appareil génital mâle Pathologie de l'appareil urinaire Pathologie de la prostate Tumeur maligne
- Mot clé (en)
- Prostate cancer Cancerology Carcinogenesis Castration C-Onc gene Human Established cell line Nephrology Treatment resistance Urology Ezh2 gene Cancer Genetics Male genital diseases Urinary system disease Prostate disease Malignant tumor
- Mot clé (es)
- Cáncer de la próstata Cancerología Carcinogénesis Castración Gen onc celular Hombre Línea celular establecida Nefrología Resistencia tratamiento Urología Cáncer Genética Aparato genital macho patología Aparato urinario patología Prostata patología Tumor maligno
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B14 Nephrologie. Maladies des voies urinaires / 002B14D Tumeurs de l'appareil urinaire / 002B14D02 Voies urinaires. Prostate
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B20 Gynecologie. Andrologie. Obstetrique / 002B20B Pathologie de l'appareil génital mâle / 002B20B02 Tumeurs
- Discipline
- Gynecology. Andrology. Obstetrics Nephrology. Urinary tract diseases
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 26762457
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1227604 
https://dx.doi.org/10.1126/science.1227604
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