In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
- Auteur
- CONDRA, J. H1 ; SCHLEIF, W. A1 ; TITUS, D; TAO YANG; TEPPLER, H; SQUIRES, K. E; DEUTSCH, P. J; EMINI, E. A; BLAHY, O. M1 ; GABRYELSKI, L. J1 ; GRAHAM, D. J1 ; QUINTERO, J. C1 ; RHODES, A1 ; ROBBINS, H. L1 ; ROTH, E; MALATHI SHIVAPRAKASH
[1] Merck Research Laboratories, dep. antiviral res., West Point PA 19486, United States - Source
Nature (London). 1995, Vol 374, Num 6522, pp 569-571 ; ref : 28 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Domaine scientifique
- Multidisciplinary
- Editeur
- Nature Publishing, London
- Pays de publication
- United Kingdom
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Antiviral Chimiothérapie Homme In vivo Inhibiteur enzyme Isolat clinique Mutation Proteinases Résistance multiple Traitement Variant Virus HIV1 L 735524 Protéine PR Enzyme Hydrolases Lentivirinae Retroviridae Virus immunodéficience humaine Virus
- Mot clé (en)
- Antiviral Chemotherapy Human In vivo Enzyme inhibitor Clinical isolate Mutation Proteinases Multiple resistance Treatment Variant HIV-1 virus Enzyme Hydrolases Lentivirinae Retroviridae Human immunodeficiency virus Virus
- Mot clé (es)
- Antiviral Quimioterapia Hombre In vivo Inhibidor enzima Aislado clinico Mutación Proteinases Resistencia múltiple Tratamiento Variante HIV-1 virus Enzima Hydrolases Lentivirinae Retroviridae Human immunodeficiency virus Virus
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02S Antibiotiques. Antiinfectieux. Antiparasitaires / 002B02S05 Antiviraux
- Discipline
- Pharmacological treatments
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 3466577
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/374569a0 
https://dx.doi.org/10.1038/374569a0
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