Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?STEINBERG, Daniel; WITZTUM, Joseph L.Circulation (New York, N.Y.). 2002, Vol 105, Num 17, pp 2107-2111, issn 0009-7322Article

History of Discovery: Oxidized Low-Density Lipoprotein and AtherosclerosisSTEINBERG, Daniel; WITZTUM, Joseph L.Arteriosclerosis, thrombosis, and vascular biology. 2010, Vol 30, Num 12, pp 2311-2316, issn 1079-5642, 6 p.Article

Evidence Mandating Earlier and More Aggressive Treatment of HypercholesterolemiaSTEINBERG, Daniel; GLASS, Christopher K; WITZTUM, Joseph L et al.Circulation (New York, N.Y.). 2008, Vol 118, Num 6, pp 672-677, issn 0009-7322, 6 p.Article

Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient miceTSIMIKAS, Sotirios; PALINSKI, Wulf; WITZTUM, Joseph L et al.Arteriosclerosis, thrombosis, and vascular biology. 2001, Vol 21, Num 1, pp 95-100, issn 1079-5642Article

Inhibition of the renin-angiotensin system abolishes the proatherogenic effect of uremia in apolipoprotein E-deficient miceBRO, Susanne; BINDER, Christoph J; WITZTUM, Joseph L et al.Arteriosclerosis, thrombosis, and vascular biology. 2007, Vol 27, Num 5, pp 1080-1086, issn 1079-5642, 7 p.Article

Relationship of a comprehensive panel of plasma oxidized low-density lipoprotein markers to angiographic restenosis in patients undergoing percutaneous coronary intervention for stable anginaSEGEV, Amit; STRAUSS, Bradley H; WITZTUM, Joseph L et al.The American heart journal. 2005, Vol 150, Num 5, pp 1007-1014, issn 0002-8703, 8 p.Article

Antisense oligonucleotides for the treatment of dyslipidaemiaVISSER, Maartje E; WITZTUM, Joseph L; STROES, Erik S. G et al.European heart journal. 2012, Vol 33, Num 12, pp 1451-1458, issn 0195-668X, 8 p.Article

Circulating oxidized low-density lipoprotein is increased in hypertensionFROSTEGARD, Johan; RUIHUA WU; LEMNE, Carola et al.Clinical science (1979). 2003, Vol 105, Num 5, pp 615-620, issn 0143-5221, 6 p.Article

Maternal hypercholesterolemia enhances atherogenesis in normocholesterolemic rabbits, which is inhibited by antioxidant or lipid-lowering intervention during pregnancy an experimental model of atherogenic mechanisms in human fetusesNAPOLI, Claudio; WITZTUM, Joseph L; CALARA, Federico et al.Circulation research. 2000, Vol 87, Num 10, pp 946-952, issn 0009-7330Article

Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosusSOEP, Jennifer B; MIETUS-SNYDER, Michele; MALLOY, Mary J et al.Arthritis care and research. 2004, Vol 51, Num 3, pp 451-457, issn 0893-7524, 7 p.Article

Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T Helper-1 Adaptive ImmunityHILGENDORF, Ingo; THEURL, Igor; ZIRLIK, Andreas et al.Circulation (New York, N.Y.). 2014, Vol 129, Num 16, pp 1677-1687, issn 0009-7322, 11 p.Article

Increased Expression of Oxidation-Specific Epitopes and Apoptosis Are Associated With Haptoglobin Genotype: Possible Implications for Plaque Progression in Human AtherosclerosisPURUSHOTHAMAN, K-Raman; PURUSHOTHAMAN, Meerarani; KINI, Annapoorna et al.Journal of the American College of Cardiology. 2012, Vol 60, Num 2, pp 112-119, issn 0735-1097, 8 p.Article

ABCA1 and ABCG1 Protect Against Oxidative Stress-Induced Macrophage Apoptosis During EfferocytosisYVAN-CHARVET, Laurent; PAGLER, Tamara A; SEIMON, Tracie A et al.Circulation research. 2010, Vol 106, Num 12, pp 1861-1869, issn 0009-7330, 9 p.Article

Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the rote of IL-10KELLY, John A; GRIFFIN, Mary E; FAVA, Roy A et al.Cardiovascular research. 2010, Vol 85, Num 1, pp 224-231, issn 0008-6363, 8 p.Article

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1: Possible Mechanism for Acceleration of Atherosclerosis by Subclinical EndotoxemiaWIESNER, Philipp; CHOI, Soo-Ho; MILLER, Yury I et al.Circulation research. 2010, Vol 107, Num 1, pp 56-65, issn 0009-7330, 10 p.Article

Lipoprotein Management in Patients With Cardiometabolic Risk : Consensus statement from the American Diabetes Association and the American College of Cardiology FoundationBRUNZELL, John D; DAVIDSON, Michael; FURBERG, Curt D et al.Diabetes care. 2008, Vol 31, Num 4, pp 811-822, issn 0149-5992, 12 p.Article

The Influence of Pravastatin and Atorvastatin on Markers of Oxidative Stress in Hypercholesterolemic HumansKY, Bonnie; BURKE, Anne; TSIMIKAS, Sotirios et al.Journal of the American College of Cardiology. 2008, Vol 51, Num 17, pp 1653-1662, issn 0735-1097, 10 p.Article

C-reactive protein, an 'intermediate phenotype' for inflammation : human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/β-adrenergic pathway loci. CommentaryTREMBLAY, Johanne; WESSEL, Jennifer; HUANG, Pauline et al.Journal of hypertension. 2007, Vol 25, Num 2, issn 0263-6352, 281-283,329-343 [18 p.]Article

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheromaAIKAWA, Masanori; SUGIYAMA, Seigo; HILL, Christopher C et al.Circulation (New York, N.Y.). 2002, Vol 106, Num 11, pp 1390-1396, issn 0009-7322Article

Targeting APOC3 in the Familial Chylomicronemia SyndromeGAUDET, Daniel; BRISSON, Diane; WITZTUM, Joseph L et al.The New England journal of medicine. 2014, Vol 371, Num 23, pp 2200-2206, issn 0028-4793, 7 p.Article

Oxidation-Specific Biomarkers, Lipoprotein(a), and Risk of Fatal and Nonfatal Coronary EventsTSIMIKAS, Sotirios; MALLAT, Ziad; KHAW, Kay-Tee et al.Journal of the American College of Cardiology. 2010, Vol 56, Num 12, pp 946-955, issn 0735-1097, 10 p.Article

Targeted Molecular Probes for Imaging Atherosclerotic Lesions With Magnetic Resonance Using Antibodies That Recognize Oxidation-Specific EpitopesBRILEY-SAEBO, Karen C; SHAW, Peter X; MULDER, Willem J. M et al.Circulation (New York, N.Y.). 2008, Vol 117, Num 25, pp 3206-3215, issn 0009-7322, 10 p.Article

Phosphorylcholine-targeting immunization reduces atherosclerosis. CommentaryCALIGIURI, Giuseppina; KHALLOU-LASCHET, Jamila; HARTVIGSEN, Karsten et al.Journal of the American College of Cardiology. 2007, Vol 50, Num 6, pp 540-550, issn 0735-1097, 11 p.Article

A natural antibody to oxidized cardiolipin binds to oxidized low-density lipoprotein, apoptotic cells, and atherosclerotic lesionsTUOMINEN, Anu; MILLER, Yury I; HANSEN, Lotte F et al.Arteriosclerosis, thrombosis, and vascular biology. 2006, Vol 26, Num 9, pp 2096-2102, issn 1079-5642, 7 p.Article

Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophagesBOULLIER, Agnès; YANKUN LI; QUEHENBERGER, Oswald et al.Arteriosclerosis, thrombosis, and vascular biology. 2006, Vol 26, Num 5, pp 1169-1176, issn 1079-5642, 8 p.Article